产品货号：
Z25582
中文名称：
REDD1/DDIT4抗体
英文名称：
Anti-REDD1/DDIT4 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-REDD1/DDIT4 Antibody |
| 指标别名 | DDIT4;Dig2;REDD 1;REDD1;REDD1 specific;RP11 442H21.1;RTP801 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | DDIT4 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | RTP801 antibody was raised against a 12 amino acid synthetic peptide from near the center of human RTP801.The immunogen is located within amino acids 90 - 140 of RTP801. |
| 计算分子量 | 25kDa |
| 成分 | RTP801 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | RTP801 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | RTP801 was initially identified as a gene induced by DNA damage,and later found to also be regulated by other cellular stresses such as hypoxia and glucocorticoid treatment.Recently,RTP801 has been shown to act as a mediator of tuberous sclerosis complex (TSC)-dependent regulation of the mammalian Target of Rapamycin (mTOR),an evolutionarily conserved serine/threonine kinase that regulates cell growth and cell cycle.In response to energy stress,RTP801 inhibits mTOR function,resulting in dephosphorylation of downstream targets such as ribosomal protein S6 kinase 1 and 4EBP1 and decreasing cell growth.Disregulation of RTP801 may thus contribute to human tumorigenesis. |
| Uniprot ID | Q9NX09 |
| 基因名全称 | DNA-damage-inducible transcript 4 |
| 蛋白名全称 | DNA-damage-inducible transcript 4 |
| 推荐稀释比 | RTP801 antibody can be used for the detection of RTP801 by Western blot at 0.5 ～ 1μg/mL.Antibody can also be used for immunohistochemistry starting at 5μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples.All other applications and species not yet tested. |
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